Korean J Med > Volume 87(2); 2014 > Article
The Korean Journal of Medicine 2014;87(2):229-233.
Published online August 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.2.229   
A Case of Complete Remission of Mucosa-associated Lymphoid Tissue Lymphoma of the Urinary Bladder after Eradication of Helicobacter Pylori
Sunpyo Lee1, Myung-soo Choo2, Min-hee Ryu1, Minjeong Song3, Seyoung Seo1, Yumun Jeong1, Myeongsook Seo1, Jooryung Huh3
1Departments of Internal Medicine, Asan medical Center,University of Ulsan College of Medicine, Seoul, Korea
2Departments of Urology, Asan medical Center, University of Ulsan College of Medicine, Seoul, Korea
3Departments of Pathology, Asan medical Center, University of Ulsan College of Medicine, Seoul, Korea
헬리코박터 제균 치료 후 완전 관해된 방광의 원발성 점막연관 림프조직 림프종 1예
이선표1, 주명수2, 류민희1, 송민정3, 서세영1, 정유문1, 서명숙1, 허주영3
1울산대학교 의과대학 서울아산병원 내과
2울산대학교 의과대학 비뇨기과
3울산대학교 의과대학 병리과
Correspondence: 
Min-hee Ryu, Tel: +82-2-3010-6961, Fax: +82-2-3010-5935, Email: miniryu@amc.seoul.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Primary lymphoma of the urinary bladder is rare, comprising 0.2% of extranodal lymphomas. The predominant subtype of mucosa-associated lymphoid tissue (MALT) is extranodal marginal zone lymphoma. We report a case of MALT lymphoma of the urinary bladder in a 53-year-old female patient presenting with a five-year history of persistent hematuria and urinary frequency. A cystoscopy revealed multiple nodular lesions at the posterior wall and trigone of the bladder. The tissue obtained by cold-cup biopsy revealed lymphoid infiltration consistent with low-grade MALT lymphoma. Image studies revealed that the tumor originated from the urinary bladder and there was no evidence of metastases. The patient was positive for a rapid urease test. Because of the relationship between gastric MALT lymphoma and Helicobacter pylori, the patient was treated with antibiotics to eradicate Helicobacter pylori. The lymphoma subsequently disappeared and the patient has remained in persistent complete remission for eight years.
Key Words: Urinary Bladder; Lymphoma; Mucosa-associated Lymphoid Tissue; Helicobacter pylori; Antibiotics
주제어: 방광; 점막연관 림프조직 림프종; 헬리코박터, 항생제


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