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Korean J Med > Volume 87(1); 2014 > Article
The Korean Journal of Medicine 2014;87(1): 101-104.
골수 외 골 종괴를 동반한 필라델피아 염색체 양성 급성 림프모구백혈병
이호진, 이혜정, 박인철, 이지현, 김성현
동아대학교 의과대학 내과학교실
A Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia in an Adult Presenting with an Extramedullary Bone Tumor
Ho Jin Lee, Hye Jung Lee, In Chul Park, Ji Hyun Lee, Sung-Hyun Kim
Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea
Corresponding Author: Sung-Hyun Kim ,Tel: +82-51-240-2608, Fax: +82-51-246-5044, Email: kshmoon@dau.ac.kr
Received: October 1, 2013;   Revised: October 22, 2013;   Accepted: October 29, 2013.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Acute lymphoblastic leukemia (ALL) is a lymphoid malignancy characterized by impaired differentiation and proliferation of leukemic myeloblasts. Normal hematopoietic cells are replaced by excess myeloblasts, causing bone marrow failure. Therefore, patients with ALL typically present with symptoms related to infection, anemia, and thrombocytopenia. Extramedullary involvement of ALL as an initial presenting symptom has rarely been reported in adults, although several such cases of relapse have been described. Isolated extramedullary manifestations may lead to a late diagnosis of ALL. We describe herein a patient with Philadelphia chromosome-positive ALL presenting with an extramedullary bone tumor.
Keywords: Acute lymphoblastic leukemia; Extramedullary diasease
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