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Korean J Med > Volume 86(5); 2014 > Article
The Korean Journal of Medicine 2014;86(5): 627-631.
신이식 후 거대세포바이러스 감염을 동반한 감염성 심내막염 1예
홍문기1, 김도형1, 김채림1, 홍준화2, 김미경3, 김수현1
1중앙대학교 의과대학 내과학교실
2중앙대학교 의과대학 흉부외과학교실
3중앙대학교 의과대학 병리학교실
A Case of Infective Endocarditis with Cytomegalovirus Infection after Kidney Transplantation
Moon-Ki Hong1, Do-Hyoung Kim1, Chae-Rim Kim1, Joonhwa Hong2, Mi-Kyung Kim3, Su-Hyun Kim1
1Departments of Internal Medicine, Departments of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
2Departments of Internal Medicine, Departments of Thoracic and Cardiovascular Surgery, Chung-Ang University College of Medicine, Seoul, Korea
3Departments of Internal Medicine, Departments of Pathology Chung-Ang University College of Medicine, Seoul, Korea
Corresponding Author: Su-Hyun Kim ,Tel: +82-2-6299-1440, Fax: +82-2-812-0853, Email: sh76so@cau.ac.kr
Received: June 7, 2013;   Revised: July 31, 2013;   Accepted: September 9, 2013.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Advances in immunosuppressive therapy have increased the survival of kidney transplant recipients, yet suppression of the immune system after transplantation can promote infectious complications. Cytomegalovirus (CMV) infection remains one of the most important complications following kidney transplantation and it is a risk factor for developing superinfections with other organisms. Aspergillus endocarditis is a rare life‐threatening complication in kidney transplantation. Coinfection of CMV and Aspergillus endocarditis is rare worldwide and has not been reported in Korea. We report a case of Aspergillus endocarditis that developed in a patient with CMV infection after kidney transplantation. His clinical condition did not improve despite mitral valve replacement and empirical antibiotic treatment, but he was eventually treated successfully with antifungal agents for 6 weeks. (Korean J Med 2014;86:627-631)
Keywords: Aspergillus; Cytomegalovirus; Endocarditis; Kidney transplantation
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