Korean J Med > Volume 86(5); 2014 > Article
The Korean Journal of Medicine 2014;86(5):603-607.
Published online May 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.86.5.603   
A Gangliocytic Paraganglioma Presenting as a Submucosal Tumor in the Ampulla
Jae Hoon Yang1, Young Koog Cheon1, Tae Yoon Lee1, Chan Sup Shim1, Wook Youn Kim2
1Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea
2Departments of Pathology, Konkuk University School of Medicine, Seoul, Korea
바터팽대부에 점막하 종양으로 보인 신경절세포 부신경절종 1예
양재훈1, 천영국1, 이태윤1, 심찬섭1, 김욱연2
1건국대학교 의과대학 내과학교실
2건국대학교 의과대학 병리학교실
Correspondence: 
Young Koog Cheon, Tel: +82-2-2030-7747, Fax: +82-2-2030-7748, Email: 20110235@kuh.ac.kr
Received: 26 August 2013   • Revised: 24 September 2013   • Accepted: 28 October 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
A gangliocytic paraganglioma (GP) is a rare benign neuroendocrine tumor. However, its origin remains unclear. It is seen most frequently in the second portion of the duodenum. At endoscopy, a GP characteristically appears as a pedunculated nodular submucosal tumor with erosions and surface ulcers. The histological diagnosis is usually made from endoscopic biopsies showing the presence of epithelioid, spindle, and ganglion cells. We experienced a case of GP in a 38-year-old female who was referred because of a possible ampullary tumor. The endoscopic images showed a 1.5-cm, oval ampullary tumor covered with normal mucosa. An endoscopic biopsy showed chronic duodenitis. The tumor was removed by an endoscopic papillectomy. We report a case of duodenal GP that presented as a submucosal tumor that was treated with a papillectomy and review the literature. (Korean J Med 2014;86:603-607)
Key Words: Paraganglioma; Gangliocytic; Endoscopic mucosal resection
주제어: 신경절세포 부신경절종; 내시경 점막 절제술


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