Korean J Med > Volume 86(5); 2014 > Article
The Korean Journal of Medicine 2014;86(5):593-597.
Published online May 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.86.5.593   
Multiple Gastrointestinal Tract MALT Lymphomas with Bone Marrow Involvement: A Case Report and Literature Revie
Hyung Jun Kim1, Jongha Park1, Young-Don Joo1, Soon Il Lee1, Eun Ji Lee1, Hyun Tae Kim1, Ji Yeon Kim2
1Departments of Internal Medicine Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea
21Departments of Internal Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea
골수를 침범한 다발성 위장관 MALT 림프종
김형준1, 박종하1, 주영돈1, 이순일1, 이은지1, 김현태1, 김지연2
1인제대학교 해운대백병원 내과
2인제대학교 해운대백병원 병리과
Correspondence: 
Jongha Park, Tel: +82-51-797-0221, Fax: +82-51-797-0941, Email: neakker@gmail.com
Received: 1 October 2013   • Revised: 29 October 2013   • Accepted: 18 November 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The stomach is the most common site of gastrointestinal tract lymphoma, while synchronous mucosa-associated lymphoid tissue (MALT) lymphomas of the stomach and duodenum are very rare. A literature review found no reported case of synchronous gastroduodenal MALT lymphomas with involvement of the bone marrow and spleen. Here, we describe the case of a 62-year-old male who was diagnosed with synchronous MALT lymphomas of the stomach and duodenum based on upper gastrointestinal endoscopy and pathology. Other staging evaluations, including colonoscopy, abdominopelvic and chest computed tomography (CT), 18F fludeoxyglucose- positron emission tomography (FDG-PET), and a bone marrow examination, showed involvement of the bone marrow and spleen. We diagnosed stage EIV MALT lymphoma and began systemic chemotherapy. We report the first case of MALT lymphomas arising synchronously in both the stomach and duodenum with bone marrow involvement and review the literature. (Korean J Med 2014;86:593-597)
Key Words: Marginal zone B cell lymphoma; Bone marrow; Stomach and duodenum
주제어: MALT 림프종; 골수; 위와 십이지장


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