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The Korean Journal of Medicine 2011;80(2): 295-300.
혈뇨 환자의 골반강에서 발견된 악성 위장관외 기질종양 1예
곽명옥1, 조소영1, 김정아1, 이혜경2, 이홍기1
A Case of an Extragastrointestinal Stromal Tumor of the Pelvic Cavity Presenting with Hematuria
Myoung Ok Kwak1, So Young Jo1, Jung A Kim1, Hye Kyung Lee2, Hong Gi Lee1
ABSTRACT
Although gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, it also occurs in the non-gastrointestinal tract, and is referred to as extragastrointestinal stromal tumor (EGIST). In this report, we describe a 48-year-old female patient who presented with hematuria, and who was finally diagnosed with a primary extragastrointestinal stromal tumor of the pelvic cavity involving the bladder, vagina and left ureter. Tumor cells were positive for immunohistochemical staining for CD117 antigen (proto-oncogene protein c-kit), CD34, and vimentin, whereas they were negative for desmin, smooth muscle actin, and S-100 protein. These findings provide histopathological and immunohistochemical evidence for diagnosing this tumor as EGIST.
Keywords: Gastrointestinal stromal tumor; Proto-oncogene protein c-kit; Pelvic cavity
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