Korean J Med > Volume 80(2); 2011 > Article
The Korean Journal of Medicine 2011;80(2):295-300.
A Case of an Extragastrointestinal Stromal Tumor of the Pelvic Cavity Presenting with Hematuria
Myoung Ok Kwak1, So Young Jo1, Jung A Kim1, Hye Kyung Lee2, Hong Gi Lee1
혈뇨 환자의 골반강에서 발견된 악성 위장관외 기질종양 1예
곽명옥1, 조소영1, 김정아1, 이혜경2, 이홍기1
Abstract
Although gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, it also occurs in the non-gastrointestinal tract, and is referred to as extragastrointestinal stromal tumor (EGIST). In this report, we describe a 48-year-old female patient who presented with hematuria, and who was finally diagnosed with a primary extragastrointestinal stromal tumor of the pelvic cavity involving the bladder, vagina and left ureter. Tumor cells were positive for immunohistochemical staining for CD117 antigen (proto-oncogene protein c-kit), CD34, and vimentin, whereas they were negative for desmin, smooth muscle actin, and S-100 protein. These findings provide histopathological and immunohistochemical evidence for diagnosing this tumor as EGIST.
Key Words: Gastrointestinal stromal tumor; Proto-oncogene protein c-kit; Pelvic cavity


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