Acute Hemorrhagic Colitis Associated with the Use of Oseltamivir

Korean J Med > Volume 80(2); 2011 > Article

Original Article

The Korean Journal of Medicine 2011;80(2):87-90.

Acute Hemorrhagic Colitis Associated with the Use of Oseltamivir

Duk Won Chung, Hyuk Su Son, Jae Hyung Park, Min Kyu Jung, Seong Woo Jeon, Chang Min Cho, Sung Kook Kim

Oseltamivir에 의해 유발된 급성 출혈성 대장염 1예

정덕원, 손혁수, 박재형, 정민규, 전성우, 조창민, 김성국

Abstract

Oseltamivir is a potent selective neuraminidase enzyme inhibitor and effective against nearly all strains of influenza A and B. The importance of treating influenza has been recognized, and oseltamivir has been prescribed frequently at the onset of the H1N1 influenza A pandemic this year. However, oseltamivir can cause hemorrhagic colitis as a rare adverse effect. Until now, only two cases of hemorrhagic colitis following the use of oseltamivir have been reported in Japan, and none have been reported in Korea. We report a case of acute hemorrhagic colitis in a 15-year-old boy after the oral administration of oseltamivir for swine originating influenza A.

Key Words: Swine-origin influenza A (H1N1); Oseltamivir; Hemorrhagic colitis