Korean J Med > Volume 78(6); 2010 > Article
The Korean Journal of Medicine 2010;78(6):751-755.
Pulmonary choriocarcinoma presenting as multiple centrilobular nodules
Mi Hyun Kim, Seong Hoon Yoon, Hee Yun Seol, Ki Uk Kim, Hye Kyung Park, Min Ki Lee, Soon Kew Park
전남대학교 의과대학 알레르기내과
다발성 중심소엽성 결절로 보인 폐 융모막 암종 1예
김미현, 윤성훈, 설희윤, 김기욱, 박혜경, 이민기, 박순규
Division of Allergy, Asthma and Clinical Immunology, Department of Internal Medicine, Chonnnam National University Medical School, Gwangju, Korea
Abstract
Choriocarcinoma, a type of germ cell tumor, follows molar pregnancy and gestational events, including abortion and ectopic pregnancy, with significantly elevated serum human chorionic gonadotropin (HCG) levels. Choriocarcinoma is rare, but very aggressive. The most common sites of metastatic involvement are the lung, vagina, and pelvic organs. We report the case of a 54-year-old woman with choriocarcinoma metastatic to the lung, with significant elevation of the serum HCG (>1,000,000 mIU/mL). Chest computed tomography (CT) on admission revealed multiple centrilobular nodules. The pathological examination of the specimen revealed tumor cell emboli in the pulmonary artery. (Korean J Med 78:751-755, 2010)
Key Words: Choriocarcinoma; Pulmonary nodule; Embolic tumor cells


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