Korean J Med > Volume 78(5); 2010 > Article
The Korean Journal of Medicine 2010;78(5):654-659.
A case of sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage
Jung-Yeon Han, Min-Keun Cho, Hyun-Sook Kim
을지대학교 을지대학병원 1내과, 충북대학교 의과대학 2내과학교실, 3병리학교실
급성 세뇨관괴사와 폐출혈을 동반하여 나타난 폐실질 침범형 유육종증 1예
한정연, 조민근, 김현숙
1Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon; Departments of 2Internal Medicine and 3Pathology, Chungbuk National University College of Medicine, Cheongju, Korea
Abstract
Sarcoidosis is a multisystemic granulomatous disorder that commonly involves the lungs, skin, and eyes. The coexistence of sarcoidosis with a kidney disorder and pulmonary hemorrhage is extremely rare. Hypercalciuria and hypercalcemia are the most common manifestations of renal involvement, although granulomatous interstitial nephritis, glomerular disease, and obstructive uropathy also occur in sarcoidosis. Acute tubular necrosis associated with acute renal failure generally shows early remission. In Korea, no cases of sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage have been reported. Here, we describe the case of a 65-year-old man with stage 3 sarcoidosis associated with acute tubular necrosis and pulmonary hemorrhage. The patient was treated with steroid and hydroxychloroquine for approximately 1 month. Most of his symptoms improved gradually, and he has been symptom-free since then. (Korean J Med 78:654-659, 2010)
Key Words: Sarcoidosis; Acute tubular necrosis; Pulmonary hemorrhage


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