| Drug therapy of gastroesophageal reflux disease: Good treatment strategies in Korea and recently developed drugs |
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Han Seung Ryu, Suck Chei Choi |
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고신대학교 의과대학 복음병원 내과 |
| 위식도역류질환의 약물치료: 국내에 좋은 치료법 및 최근의 개발약물 |
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류한승, 최석채 |
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Department of Internal Medicine, Kosin University College of Medicine, Gospel Hospital, Busan, Korea |
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| Abstract |
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The prevalence of gastroesophageal reflux disease (GERD) in Western countries ranges between 10% and 20%. Although GERD is increasing in Korea, it is difficult to actively conduct studies due to restrictions in insurance regulations and there are practical limitations to prescribe drugs conforming the evidence-based guidelines. As novel drug therapy for GERD, drugs with new mechanisms that would overcome pharmacokinetic limits of proton pump inhibitors are being investigated. In this review, with regards to drug therapy of GERD, we discuss management strategies suitable for domestic circumstances and drugs that are being newly developed. (Korean J Med 78:155-162, 2010) |
| Key Words:
Gastroesophageal reflux disease; Drug therapy |
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