A case of megaloblastic anemia presented as pancytopenia and increased serum vitamin B12 level |
Sun Hee Beom, Jae Myung Lee, Sang Hyuk Lee, Suk Ho Hong, Ho Jun Lee, Dae Hee Lee, Seong Min Yoon |
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범혈구감소증과 높은 혈청 비타민 B12 농도를 보인 거대적아구성 빈혈 1예 |
범선희·이재명·이상혁·홍석호·이호준·이대희·윤성민, Jae Myung Lee, Sang Hyuk Lee, Suk Ho Hong, Ho Jun Lee, Dae Hee Lee, Seong Min Yoon |
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Abstract |
Low serum vitamin B12 (cobalamin) level is a valuable indicator of cobalamin-deficiency megaloblastic anemia, which sometimes
presents as pancytopenia. It can also be diagnosed by cobalamin deficiency if the patient shows related clinical symptoms and
increased serum homocysteine or urine methylmalonic acid, metabolites of cobalamin, although the serum cobalamin level may be
normal. We report a case of cobalamin-deficiency megaloblastic anemia presenting as pancytopenia with an increased serum vitamin
B12 level. (Korean J Med 77:S1314-S1317, 2009) |
Key Words:
Vitamin B12 deficiency; Megaloblastic anemia; Pancytopenia |
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