Two cases of sarcomatoid carcinoma of the liver associated with glomerulonephritis

Ha Na Park,; Jong Won Choi,; Jun Yong Park,; Young Nyun Park,; Do Young Kim,; Kwang-Hyub Han,; Chae Yoon Chon,

Korean J Med > Volume 77(1); 2009 > Article

Original Article

The Korean Journal of Medicine 2009;77(1):1-6.

Two cases of sarcomatoid carcinoma of the liver associated with glomerulonephritis

Ha Na Park, Jong Won Choi, Jun Yong Park, Young Nyun Park, Do Young Kim, Kwang-Hyub Han, Chae Yoon Chon

사구체신염과 동반하여 발생한 간내 육종양 암종 2예

박하나, 최종원, 박준용, 박영년, 김도영, 한광협, 전재윤

Abstract

Sarcomatoid carcinoma is a rare malignant neoplasm that may develop in various organs. Hepatocellular carcinoma with sarcomatous changes after anticancer therapy, such as hepatic arterial chemoembolization, has been reported, but primary sarcomatoid carcinoma of the liver is uncommon. Here, we report two cases of primary liver sarcomatoid carcinoma associated with glomerulonephritis in two men (68 and 55 years old, respectively) without any risk factors. Neither man was an alcoholic nor a hepatitis virus carrier, nor did either have a prior medical history of disease. Tumor markers were within normal ranges. In both men, imaging studies revealed a mass in the liver, with metastatic lesions on either the lung or sacrum, respectively. Histopathologic examination of the liver and kidney revealed sarcomatoid carcinoma of the liver and glomerulonephritis.

Key Words: Sarcoma; Liver; Glomerulonephritis