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Churg-Strauss syndrome is a rare systemic necrotizing vasculitis that is characterized by asthma, peripheral eosinophilia, non-fixed pulmonary infiltrates, neuropathy and histopathologic features of extravascular eosinophilic infiltration and granuloma formation. Churg-Strauss syndrome is accompanied by asthma in nearly all cases. However, a few atypical cases of Churg-Strauss syndrome without asthma or eosinophilia have been reported. An 18-year-old male was referred for discoloration of right second finger, and right foot drop. He developed peripheral eosinophilia, bilateral pulmonary infiltrates, mononeuritis multiplex, extravascular eosinophilic infiltration on lung biopsy, and vasculitis on medium to small sized arteries of upper and lower extremities without asthma. We report an atypical case of an 18-year-old male patient diagnosed as Churg-Strauss syndrome without preexisting asthma. |
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