| Home | E-Submission | Sitemap | Contact Us |  
logo
The Korean Journal of Medicine 2009;77(4): 383-400.
만성폐쇄성폐질환의 병인과 병태생리
유 철 규
Pathogenesis and pathophysiology of COPD
Chul-Gyu Yoo
ABSTRACT
Chronic obstructive pulmonary disease (COPD) is a slowly progressed disease characterized by chronic irreversible airway obstruction with increased airway resistance and loss of elastic recoil by lung parenchymal destruction. COPD is a leading cause of morbidity and mortality worldwide. COPD is defined as a preventable and treatable disease with some significant extrapulmonary effects that may contribute to the severity in individual patients. Pathological changes characteristic of COPD are found in the proximal airways, peripheral airways, lung parenchyma, and pulmonary vasculature, showing chronic inflammation, and structural changes resulting from repeated injury and repair mostly caused by inhaled cigarette smoke. This pathological changes lead to airway trapping and progressive airway limitation. (Korean J Med 77:383-400, 2009)
Keywords: Chronic obstructive pulmonary disease; Pathogenesis; Physiology
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Supplementary Material  Supplementary Material
  E-Mail
Share:      
METRICS
1,061
View
48
Download
Pathophysiology of Colon Diverticulum  2013 December;85(6)
Etiology, Pathogenesis and Natural Course of Chronic Pancreatitis  2012 July;83(1)
Pathophysiology of Gout  2011 March;80(3)
Pathogenesis and pathophysiology of pulmonary arterial hypertension  2010 January;78(1)
Pathogenesis of diabetic nephropathy  2009 December;77(6)
Editorial Office
101-2501, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-2271-6791   Fax: +82-2-790-0993    E-mail: kaim@kams.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © The Korean Association of Internal Medicine. All rights reserved.                powerd by m2community