Influence of multiple insulin injections on quality of life, anxiety levels, and depression in type 2 diabetics

Ye-Ree Park,; Tae-Suk Kim,; Yong-Gyu Park,; Seong-Su Lee,; Sung-Rae Kim,; Hyun-Shik Son,; Kun-Ho Yoon,; Moo-Il Kang,; Bong-Youn Cha,; Kwang-Woo Lee,; Ho-Young Son,; Sung-Koo Kang,; Soon-Jib Yoo,

Korean J Med > Volume 77(1); 2009 > Article

Original Article

The Korean Journal of Medicine 2009;77(1):60-67.

Influence of multiple insulin injections on quality of life, anxiety levels, and depression in type 2 diabetics

Ye-Ree Park, Tae-Suk Kim, Yong-Gyu Park, Seong-Su Lee, Sung-Rae Kim, Hyun-Shik Son, Kun-Ho Yoon, Moo-Il Kang, Bong-Youn Cha, Kwang-Woo Lee, Ho-Young Son, Sung-Koo Kang, Soon-Jib Yoo

다회 인슐린 투여가 당뇨병 환자의 삶의 질, 우울 및 불안 요소에 미치는 영향

박예리, 김태석, 박용규, 이성수, 김성래, 손현식, 윤건호, 강무일, 차봉연, 이광우, 손호영, 강성구, 유순집

Abstract

Background/Aims: Treatment using multiple daily insulin (MDI) should give diabetic patients many benefits. Nevertheless, few studies have examined the impact of an increased frequency of daily insulin injection on quality of life, anxiety levels, and depression in diabetic patients, and individual’s continued compliance with MDI is unclear. This study examined these issues using standardized questionnaires. Methods: This was a cross-sectional, randomized study. Ninety-nine insulin-treated type 2 diabetic patients (mean age 53.1±12 years, mean duration of diabetes 10.3±6.5 years) were divided a group (n=50) who injected insulin four times daily (mean age 49.6±12.3 years, mean duration of diabetes 6.5±6.4 years) and a group (n=49) who injected insulin once or twice daily (mean age 56.4±11.6 years, mean duration of diabetes 11.5±5.8 years). All patients independently completed the Korean Version of the World Health Organization Quality of Life Scale Abbreviated Version and standardized Hospital Anxiety and Depression Scale for Koreans. Results: No significant differences were evident with respect to age, gender, and duration of diabetes between the two groups (p<0.05). No significant differences were evident in the results of the questionnaires between the two groups, except for the physical health domain (p<0.05). Conclusions: Multiple daily insulin injections had nearly no influence on quality of life, anxiety levels, or depression in type 2 diabetic patients. Therefore, treatment with MDI should be considered for patients who would benefit from this. (Korean J Med 77:60-67, 2009)

Key Words: Insulin; Diabetes mellitus; Quality of life; Anxiety; Depression