Focal nodular hyperplasia-like nodules in a young man with congenital liver cirrhosis

Ju Hee Seo,; Jun Yong Park,; Young Nyun Park,; Ha Na Park,; Ji Hyeon Baek,; Hye Ryun Kim,; Kwang-Hyub Han,

Korean J Med > Volume 76(1); 2009 > Article

Original Article

The Korean Journal of Medicine 2009;76(1):26-30.

Focal nodular hyperplasia-like nodules in a young man with congenital liver cirrhosis

Ju Hee Seo, Jun Yong Park, Young Nyun Park, Ha Na Park, Ji Hyeon Baek, Hye Ryun Kim, Kwang-Hyub Han

선천성 간경변증에서 발생한 국소결절증식양 결절 1예

서주희, 박준용, 박영년, 박하나, 백지현, 김혜련, 한광협

Abstract

Focal nodular hyperplasia-like nodules (FNH-like nodules) are hypervascular lesions that occur in the cirrhotic liver. Histologically, they are similar to classical FNH in an otherwise normal liver. Radiologically, FNH-like nodules may mimic hepatocellular carcinoma (HCC), and they have been misdiagnosed as HCC based on radiological findings. Their pathogenesis and etiology are unclear, but they may arise from a local hyperplastic response to vascular alterations like classical FNH. Rarely, these nodules transform into malignant tumors and cause complications. We report the case of a 28-year-old man with multiple FNH-like nodules in congenital liver cirrhosis. (Korean J Med 76:S26-S30, 2009)

Key Words: Focal nodular hyperplasia; Focal nodular hyperplasia-like nodules (FNH-like nodules); Liver cirrhosis