| Factors favoring survival in elderly patients with colorectal cancer |
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Ji Min Jung, Sung-Ae Jung, Seong-Eun Kim, Min-Jung Kang, Ki-Nam Shim, Kwang Ho Kim, Kwon Yoo, Il Hwan Moon |
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| 고령 대장암 환자에서 수술 시행에 따른 생존율의 차이와 위험인자 분석 |
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정지민, 정성애, 김성은, 강민정, 심기남, 김광호, 유 권, 문일환 |
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| Abstract |
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Background/Aims: Colorectal cancer occurs predominantly in the elderly, and whether to operate on these patients is a dilemma. This study compared clinical parameters and evaluated factors favoring survival in elderly patients with colorectal cancer according to the treatment modality.
Methods: The study evaluated 213 patients who were older than 75 years and diagnosed with colorectal cancer between 1995 and 2005. Survival rate and clinical parameters were compared between the surgical and conservative treatment groups. Demographics, underlying conditions, and cancer and treatment-related factors were evaluated for survival using multivariate analysis in the conservatively treated patients and separately in the surgery group.
Results: The surgery group consisted of 143 (67.1%) patients and the conservative group consisted of 70 (32.9%) patients. Fewer patients had a high ASA class in the surgery group than in the conservative group (p<0.05). The survival rate in the surgery group was higher than in the conservative group (p<0.05) even when compared for the same cancer stage, ASA class, and age (p<0.05). In the surgery group, the absence of history of diabetes mellitus, lower cancer stage, elective surgery, and curative surgery all favored survival (p<0.05).
Conclusions: The 5-year survival rate in the surgery group was higher than that in the conservative group. Surgery is recommended for elderly patients with colorectal cancer who are in good physical shape and have a lower stage, a resectable tumor, and a non-emergency condition.
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| Key Words:
Aged; Colorectal neoplasms; Surgery |
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