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The Korean Journal of Medicine 2008;75(3): 881-884.
증례 : 미세변화 신증후군에 동시에 병발된 뇌경색 1예
김제열.김성균, .허경림.김은정, .송영림.김형직, .남은숙, Young Rim Song, Hyug Jik Kim, Eun Sook Nam
A case of acute cerebral infarction in a patient with minimal change nephrotic syndrome
Je Yeol Kim, Sung Gyun Kim, Kung Rim Huh, Eun Jung Kim, Young Rim Song, Hyug Jik Kim, Eun Sook Nam
Nephrotic syndrome is associated with a hypercoagulable state and is a known risk factor for arterial and venous thrombosis. However, acute cerebral infarction secondary to arterial thrombosis in an adult with acute presentation of minimal change disease is rare. Here, we report the case of a 59-year-old man with acute proximal middle cerebral artery infarction within ten days of nephrotic syndrome. His clinical and pathological findings were consistent with minimal change nephrotic syndrome. The patient did not show any other predisposing factor to vascular thromboembolic events except for hypercoagulability related to nephrotic syndrome. The patient completely recovered from nephrotic syndrome and infarction upon standard treatment with prednisolone, diuretics, and antiplatelet drugs. The possible pathogenetic mechanism of this condition is discussed and the pertinent literature is reviewed. (Korean J Med 75:S881-S884, 2008)
Keywords: Cerebral embolism and thrombosis; Cerebral infarction; Minimal change nephrotic syndrome
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