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The Korean Journal of Medicine 2008;75(6): 694-699.
위 림프종으로 오인된 원발성 위 소세포암
이소영, 김진일, 김상희, 박용재, 김재광, 우인숙, 이연수
A case of gastric small cell carcinoma mimicking gastric lymphoma
So Young Lee, Jin Il Kim, Sang Hee Kim, Yong Jai Park, Jae Kwang Kim, In Sook Woo, Youn Soo Lee
경희대학교 의과대학 순환기내과학교실
ABSTRACT
Primary gastric small cell carcinoma (SmCC) is rarely encountered and has a poor prognosis, even when discovered at an early stage. A 69-year-old man presented with upper abdominal pain and melena. Endoscopic examination revealed an 8-cm-diameter submucosal tumor with ulceration high on the body of the greater curvature suggesting malignant lymphoma. Histological examination revealed a solid proliferation of small cells with hyperchromatic round nuclei and scant cytoplasm. On immunohistochemical staining, the neoplastic cells were positive for synaptophysin, EMA, and CD56. Abdominal computed tomography (CT) revealed multiple variable-sized low-attenuated masses with peripheral rim enhancement in both hepatic lobes. He was diagnosed with a pure type gastric SmCC with multiple hepatic metastasis. After systemic chemotherapy, the tumor regressed substantially on CT and endoscopy. We report a case of hepatic metastasis of gastric SmCC mimicking gastric lymphoma. (Korean J Med 75:694-699, 2008)
Keywords: Gastric cancer; Small cell carcinoma; Neuroendocrine tumor
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