Korean J Med > Volume 74(1); 2008 > Article
The Korean Journal of Medicine 2008;74(1):12-16.
A case of hepatic sarcoidosis
Byung-Hoo Lee, Han-Jo Kim, Ho-Young Lee, ., Jae-Young Jang, So-Young Jin, Chan-Sup Shim., Boo-Sung Kim.
Cardiology Division, Department of Internal Medicine, Yeungnam University Hospital1
증례 : 복부초음파상 특이소견을 보이며 간비대를 동반한 간의 유육종증 1예
이병후, 김한조, 이호영, 장재영, 진소영, 심찬섭, 김부성, Boo-Sung Kim.
Abstract
Sarcoidosis is a chronic, multi-system, granulomatous disease of unknown etiology that may involve the lung, liver, spleen, kidney, lymph node, eye, and skin. It is characterized by the presence of non-caseating granulomatous lesions in affected organs. Sarcoidosis frequently involves the liver and spleen, but hepatosplenomegaly and liver dysfunction are rare manifestations. We report the case of a 42-year-old Korean female who was diagnosed with sarcoidosis 6 years prior to presentation. She had been diagnosed with pulmonary sarcoidosis by transbronchial lung biopsy. She had been treated with methotrexate because she could not tolerate steroids. Abdominal ultrasonography on presentation revealed diffuse, heterogeneous, highly echogenic lesions of the liver. Abdominal computed tomography (CT) showed multiple, small, low density lesions in the liver and spleen. Infiltrative liver disease, particularly hepatic sarcoidosis, was suspected. Hepatic sarcoidosis was confirmed by needle biopsy of the liver.
Key Words: Hepatic Sarcoidosis, Hepatosplenomegaly


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