Korean J Med > Volume 74(5); 2008 > Article
The Korean Journal of Medicine 2008;74(5):570-573.
A case of gastric granulocytic sarcoma in a patient with transformed acute leukemia from myelodysplastic syndrome
Yong Seok Kim, Young Woo Choi, Dae Seung Im, Tae Hee Lee, Eui Hyeog Im, Kyu Chan Huh, Young Woo Kang
고려대학교 의과대학 내과학교실
증례 : 골수 이형성 증후군에서 급성 백혈병으로 전환기에 발생한 위 과립구 육종 1예
김용석, 최용우, 임대승, 이태희, 임의혁, 허규찬, 강영우
Abstract
Granulocytic sarcoma is a localized tumor that’s composed of immature cells of the granulocytic series. The tumor may be involved anywhere in the body, but we present here a rare case that involved the gastrointestinal tract (and especially the stomach). Granulocytic sarcoma may represent the initial manifestation of blast transformation or it may herald the onset of acute leukemia from myelodysplastic syndrome. We report here on a case of gastric granulocytic sarcoma in a patient with transformed acute leukemia from myelodysplastic syndrome. A 56-year-old male who was suffering with myelodysplastic syndrome (RARS) for 5 years presented with upper abdominal pain. Gastrofiberoscopy revealed an elevated lesion with central erosion at the posterior wall of the gastric upper body, which histologically proved to be a granulocytic sarcoma. The peripheral blood smear and bone marrow examination showed acute myeloid leukemia.
Key Words: Granulocytic sarcoma; Myelodysplastic syndrome; Acute myeloid leukemia


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