A case of brucella endocarditis with spondylitis in a patient with multiple myeloma |
Yung Un Kang, Young Sun Jung, Kyung Hwa Park, Sook In Jung, Jong Hee Shin, Byung Hee Anh, Kwan Soo Ko |
경희대학교 의과대학 순환기내과학교실 |
증례 : 다발성 골수종 환자에서 척추염을 동반한 브루셀라 심내막염 |
강용운, 정영선, 박경화, 정숙인, 신종희, 안병희, 고관수 |
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Abstract |
Brucella endocarditis is a rare complication, but it is responsible for the majority of deaths related to this illness. A 67 year-old man presented with complaints of fever and lower back pain that he had experienced during the previous four weeks. The laboratory finding showed pancytopenia and an inverted total protein/globulin ratio. Multiple myeloma was diagnosed by bone marrow biopsy and serum electrophorosis. The spine MRI scan demonstrated spondylitis with epidural abscess (L5-S1). On the echocardiographic examination, there was vegetation on the right coronary cusp of the aortic valve and perivalvular abscess. The blood isolate was confirmed as Brucella abortus by using DNA sequencing of the 16S rRNA and the omp2a and omp2b genes. The clinical manifestations improved after appropriate antibiotics and aortic valve replacement. We describe here the first Korean case of human brucella endocarditis that was treated by valve replacement.
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Key Words:
Kidney transplantation; Vesicoureteral reflux; Ureteroureterostomy |
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