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The Korean Journal of Medicine 2008;74(4): 418-425.
원저 : 한국인 건선관절염 환자의 임상양상 및 성별에 따른 비교
최효진, 이윤종, 박정진, 이정찬, 이은영, 이은봉, 백한주, 윤재일, 송영욱
Clinical features of Korean patients with psoriatic arthritis
Hyo Jin Choi, Yun Jong Lee, Jung Jin Park, Jung Chan Lee, Eun Young Lee, Eun Bong Lee, Han Joo Baek, Jae Il Youn, Yeong Wook Song
서울대학교 의과대학 내과학교실1, 경희대학교 의과대학 내과학교실2
ABSTRACT
Background/Aims : The aims of our study were to reassess the prevalence of psoriatic arthritis (PsA) in Korean patients with psoriasis and to evaluate their clinical features according to gender. Methods : We evaluated 156 consecutive patients with psoriasis who visited the dermatology clinic in Seoul National University Hospital between the September 2004 and January 2005. A dermatologist diagnosed psoriasis and determined its type and psoriasis area and severity index (PASI). Medical interview, joint examination and diagnosis of PsA were made by a rheumatologist. Results : Twenty-two patients (14.1%) were diagnosed with PsA among patients with psoriasis. Pustular psoriasis were more frequent in patients with PsA (47.4%) than those without arthritis (9.2%), and plaque psoriasis were less frequent in patients with PsA (42.1%) than those without arthritis (82.6%). Nail change was found in 77.3%, being more common compared to those without PsA (51.2%). Psoriasis was followed by arthritis in 81.8% of PsA patients with the interval of 15.3¡¾9.7 years (mean¡¾SD). Spondylitis was predominant (36.4%). Clinical features were similar between men and women. However, males with PsA had a shorter duration of psoriasis, and older onset of arthritis than females. Conclusion : We characterized the clinical features of PsA in Korean patients on single center base. The prevalence of PsA in patients with psoriasis was 14.1%. Plaque type psoriasis was less common and pustular psoriasis was more common in patients with PsA than those without arthritis. Males with PsA had a shorter duration of psoriasis and older onset of arthritis than females.
Keywords: Psoriatic arthritis; Prevalence; Gender
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