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The Korean Journal of Medicine 2008;74(4): 385-390.
원저 : 춘천 지역의 위식도 역류질환과 역류성 식도염의 특징-건강 검진자 연구
이주용, 홍원기, 손경민, 김대용, 김영묵, 최현희, 최창순, 김성중, 백광호, 김진봉, 김동준
Prevalence and clinical characteristics of gastroesophageal reflux disease and reflux esophagitis in chuncheon city-Health care examination study
Jue Yong Lee, Won Ki Hong, Kyung Min Sohn, Dae Yong Kim, Young Mook Kim, Hyun Hee Choi, Chang Soon Choi, Seong Jung Kim, Gwang Ho Baik, Jin Bong Kim, Dong Joon Kim
을지의과대학교 내과학교실1, 흉부외과학교실2, 영상의학교실3, 병리학교실5
ABSTRACT
Background/Aims : The aims of this study were to estimate the frequency of symptoms of gastroesophageal reflux disease and reflux esophagitis, to evaluate the difference in characteristics among groups subdivided by symptoms, and to compare clinical features between a reflux esophagitis group and a non‐reflux esophagitis group in Chuncheon City. Methods : A total of 1,011 persons who underwent endoscopy for health check‐up were enrolled between July 1, 2005, and June 30, 2006. All persons were given a validated, self‐reported questionnaire, which inquired about the presence, frequency, and severity of typical symptoms (heartburn and acid regurgitation) and atypical symptoms. The questionnaire also inquired about smoking, alcohol intake, and Helicobacter pyroli eradication. The subjects were subdivided into typical symptomatic, atypical symptomatic, no discomfort, and asymptomatic groups. Results : The prevalence of heartburn and acid regurgitation occurring at least weekly was 7.5%. Reflux esophagitis, hiatal hernia, smoking, and alcohol intake were more common in males (p<0.05). Ninety‐eight cases (9.7%) were endoscopically diagnosed as reflux esophagitis, and sixty‐nine cases (6.8%) were endoscopically suspected esophageal metaplasia (ESEM). Subjects in the symptomatic group more frequently manifested reflux esophagitis than subjects in the asymptomatic group (p<0.05). Conclusions : The presence of reflux‐induced symptoms is related to reflux esophagitis, but the intensity and frequency of symptoms are poor predictors of the presence or severity of endoscopic mucosal breaks.
Keywords: Gastroesophageal Reflux; Esophagitis; Reflux; Barrett Esophagus; Prevalence
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