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The Korean Journal of Medicine 2008;74(3): 310-314.
증례 : 재발성 췌장염으로 발현한 췌장 상피내 종양(PanIN-III) 1예
손병석 . 이성구 . 김명환 . 서동완 . 이상수 . 김송철 . 장세진, , , , , ,
A case of pancreatic intraepithelial neoplasm (PanIN-III) manifesting as recurrent pancreatitis
Byeong Seok Sohn, Sung Koo Lee, Myung Hwan Kim, Dong Wan Seo, Sang Soo Lee, Song Cheol Kim, Sae Jin Jang
경희대학교 의과대학 순환기내과학교실
ABSTRACT
Acute recurrent pancreatitis has a variety of etiologies. We experienced a case of a tumor-forming pancreatitis in a 49 year old Korean woman who also had pancreatic intraepithelial neoplasm III (PanIN-III), and this manifested just like recurrent pancreatitis. She had a history of recurrent pancreatitis. She was found to have an early stage of pancreatic cancer via computed tomography and magnetic resonance cholangiopancreatography. EUS guided fine needle aspiration (FNA) showed only many acinar cells of the pancreas. But due to the possibility of her having pancreatic carcinoma, she underwent distal pancreatectomy and splenectomy with lymph node dissection. Pathologically, the tumor of the pancreatic body showed secondary changes with focal fibrosis from the localized chronic pancreatitis. PanIN-III was observed in the pancreatic duct within the tumor, and there were no cancerous findings in the 13 dissected lymph nodes. (Korean J Med 74:310-314, 2008)
Keywords: Chronic pancreatitis; Focal fibrosis; PanIN; Recurrent pancreatitis
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