Korean J Med > Volume 74(1); 2008 > Article
The Korean Journal of Medicine 2008;74(1):106-109.
Development of juvenile rheumatoid arthritis in a patient with multiple sclerosis
Soo-Young Moon, Yeon-Ah Lee, Joonbeom Shin, Sang-Hoon Lee, Seung-Jae Hong, Hyung-In Yang
Cardiology Division, Department of Internal Medicine, Yeungnam University Hospital1
증례 : 다발성 경화증 환자에서 발병된 청소년 류마티스 관절염 1예
문수영 . 이연아 . 신준범 . 이상훈 . 홍승재 . 양형인, Yeon-Ah Lee, Joonbeom Shin, Sang-Hoon Lee, Seung-Jae Hong, Hyung-In Yang
Abstract
Multiple sclerosis (MS) is an immune-mediated, inflammatory demyelinating disease of the central nervous system. The coexistence of multiple sclerosis and rheumatoid arthritis is very rare. This rare association is interesting due to the overlapping pathophysiological similarities of T-cells and tumor necrosis factor-α (TNF-α) in both diseases. We report a case of a Korean 10‐year‐old girl with multiple sclerosis, who after 3 years developed a clinical and serological manifestation of juvenile rheumatoid arthritis. (Korean J Med 74:106-109, 2008)
Key Words: Multiple sclerosis; juvenile rheumatoid arthritis


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