A case of dermatomyositis associated with papillary carcinoma of the thyroid gland |
Bon Seung Ku, Chan Sung Park, Ji-Young Chai, Seung Won Choi, Jee-Hyun Kwon, Hee Jeong Cha |
Cardiology Division, Department of Internal Medicine, Yeungnam University Hospital1 |
증례 : 갑상샘 유두암에서 발생한 피부근육염 1예 |
구본승박찬성채지영최승원권지현차희정, Chan Sung Park, Ji-Young Chai, Seung Won Choi, Jee-Hyun Kwon, Hee Jeong Cha |
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Abstract |
Dermatomyositis is an idiopathic inflammatory myopathy with characteristic skin manifestations, including the
heliotrope rash and Gottron's papule. The association between malignancy and dermatomyositis is well established,
especially in elderly patients. However, the nature of the causal relationship underlying this association remains unknown.
Cancer may occur before the onset of dermatomyositis, concurrently, or afterward. Lung, breast, ovary, gastrointestinal
tract and lymphoproliferative disorders are the most frequently detected malignancies. However, the association between
dermatomyositis and thyroid malignancy is uncommon, and there have been few descriptions of this association.
We report an unusual case of dermatomyositis arising in a patient with papillary carcinoma of the thyroid gland. After
the tumor had been resected, the patient's skin lesions and muscle weakness began to improve, and the serum levels of
CPK, AST, and LD decreased. This case showed that the successful treatment of an underlying malignancy may lead
to the resolution of dermatomyositis.(Korean J Med 73:S1090-S1094, 2007) |
Key Words:
Dermatomyositis, Thyroid, Carcinoma, Papillary |
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