A case of suprasellar germinoma misdiagnosed as lymphocytic hypophysitis |
Guilsun Kim, Shin-Ae Park, Hui-Jeong Hwang, Jong-Yul Lee, Seung-Hyun Ko, Yu-Bai Ahn, Ki-Ho Song |
경희대학교 의과대학 순환기내과학교실 |
증례 : 임파구성 뇌하수체염으로 오인된 시상상부 배아종 1예 |
김길선, 박신애, 황희정, 이종율, 고승현, 안유배, 송기호 |
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Abstract |
We report here on a case of a 22-year-old girl with a suprasellar mass that was originally diagnosed as lymphocytic hypophysitis, but it eventually turned out to be a germinoma. She initially underwent partial tumor removal and the tissue diagnosis was suggestive of lymphocytic hypophysitis. 46 months later, she presented with a lateral visual field defect and decreased visual acuity of her right eye. The serum and cerebrospinal β-hCG and α-fetoprotein levels were measured. The β-hCG level was elevated in both, whereas the α-fetoprotein level was detectable in neither. The serum anti-pituitary antibody-1 level was negative. She was reoperated and the permanent section biopsies were compatible with pure germinoma. There was no evidence of meningeal metastasis on her whole spine MRI. She was treated with chemotherapy. (Korean J Med 73:210-215, 2007)
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Key Words:
Germinoma, Lymphocytic hypophysitis, β-hCG |
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