Clinical value of the biochemical and nutritional parameters of intensive-care unit patients on mechanical ventilation

Seo Goo Han,; Il Woon Park,; Tae Woon Park,

Korean J Med > Volume 73(2); 2007 > Article

Original Article

The Korean Journal of Medicine 2007;73(2):151-158.

Clinical value of the biochemical and nutritional parameters of intensive-care unit patients on mechanical ventilation

Seo Goo Han, Il Woon Park, Tae Woon Park, , , , , ,

전남대학교병원 심장센터, 간호부, 전남대학교 심혈관계 특성화 사업단

원저 : 기계환기 중인 중환자에서 영양생화학적 지표 측정의 의의

한서구, 박일운, 박태운, 신보경, 문동석, 김형진, 정재호, 최정은, 원영준

Abstract

Background : The nutritional status of critical-ill patients is important for recovering from the disease itself. Therefore, this present study was designed to assess the biochemical and nutritional parameters of Intensive-Care Unit (ICU) patients on mechanical ventilation. Methods : We retrospectively reviewed the medicial records of 126 patients (male/female=72/54) who were on mechanical ventilationin the ICU. The nutritional parameters such as serum total protein, albumin, hemoglobin, hematocrit, calcium, phosphorus, total cholesterol, % lymphocytes, blood urea nitrogen (BUN), and creatinine (Cr) were measured at the beginning of mechanical ventilation. We also measured the outcome variables such as the duration of mechanical ventilation, the ICU length of stay and the hospitalization period. We analyzed the relationship between the nutritional parameters and the outcome variables of ICU patients on mechanical ventilation. Results : The level of hemoglobin was negatively correlated with the outcome variables; the ICU length of stay (p<0.05), the hospitalized period (p<0.01), and the duration of mechanical ventilation (p<0.01). The creatinine level was positively correlated with the outcome variables; the ICU length of stay (p<0.01), the hospitalized period (p<0.01) and the duration of mechanical ventilation (p<0.05). On the multiple regression analysis, the serum total protein, albumin, calcium, inorganic phosphorus, BUN and creatinine were independent factors affecting the duration of mechanical ventilation. Conclusions : These findings indicate that ICU patients with mechanical ventilation have a risk for malnutrition and anemia. So, an adequate nutritional intervention is required for these patients in order to decrease the prevalence of malnutrition and anemia.(Korean J Med 73:151-158, 2007)

Key Words: Nutrition assessment, Mechanical ventilation, Malnutrition, Mnemia