A case of trousseaus syndrome associated with adenocarcinoma of the lung |
Young Jae Cho, Hee Joung Kim, Ji Eun Lee, Joon Sung Joh, Sung Koo Han, Young Soo Shim, Chul Gyu Yoo |
고려대학교 의과대학 내과학교실 |
증례 : 폐암에 동반되어 동맥 혈전색전증으로 발현된 Trousseau 증후군 1예 |
조영재, Hee Joung Kim, Ji Eun Lee, Joon Sung Joh, Sung Koo Han, Young Soo Shim, Chul Gyu Yoo |
|
|
|
Abstract |
In 1865, Armand Trousseau recognized the first relationship between a neoplastic disease and a thromboembolic disorder. Since then, many cases have been reported and have been termed as Trousseau's syndrome. One mechanism of hypercoagulability was considered to be the activation of coagulation systems by a tissue factor secreted by neoplastic cells, but accurate pathophysiology still remains unknown. We report a case of a multiple and recurrent thromboembolism in a patient with adenocarcinoma of the lung. A woman aged 68 years with an acute thromboembolism at her right distal calf artery was diagnosed as having adenocarcinoma of the lung.
She underwent a thromboembolectomy two times, but had to receive surgery for a below knee amputation. Multiple and recurrent thromboembolic events then attacked her cerebral and coronary arteries, which led to cerebral and myocardial infarctions. She expired by a progression of the adenocarcinoma of the lung after about six months.(Korean J Med 72:673-678, 2007)
Key Words : Adenocarcinoma, Lung, Trousseau's syndrome |
Key Words:
Adenocarcinoma, Lung, Trousseau's syndrome |
|