Korean J Med > Volume 88(6); 2015 > Article
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The Korean Journal of Medicine 2015;88(6):737-741.
Published online June 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.6.737   
A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis
Ji-Heh Park1, Seung-Geun Lee1, Eun-Kyoung Park1, Dong-Wan Koo1, Bo-Hyun Kim1, In-Joo Kim1, Geun-Tae Kim2
1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
2Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
강직성 척추염 환자에서 발생한 갑상선자극호르몬(TSH) 분비 뇌하수체 선종 1예
박지혜1, 이승근1, 박은경1, 구동완1, 김보현1, 김인주1, 김근태2
1부산대학교 의학전문대학원 내과학교실
2고신대학교 의과대학 내과학교실
Correspondence: 
Seung-Geun Lee, Tel: +82-51-240-7580, Fax: +82-51-241-7581, Email: sglee@pnuh.co.kr
Received: 9 October 2014   • Revised: 6 November 2014   • Accepted: 1 December 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the axial skeleton. Extra-articular manifestations, such as anterior uveitis, may also be prominent features in AS but little is known about the association between AS and thyroid diseases including TSH-secreting pituitary adenomas. We present a case study of a 26-year-old male AS patient who was diagnosed with a TSH-secreting pituitary adenoma using a thyrotropin releasing hormone stimulation test, measurement of the TSH α-subunit, and magnetic resonance imaging, and subsequently treated with a transsphenoidal tumor resection.
Key Words: Pituitary neoplasms; Thyrotropin; Spondylitis, Ankylosing
주제어: 뇌하수체샘종; 갑상샘자극호르몬; 강직척추염


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