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Korean J Med > Volume 88(3); 2015 > Article
The Korean Journal of Medicine 2015;88(3): 340-345.
낼리딕산 내성 Salmonella enteritidis에 의한 급성 대퇴골 골수염 1예
나성균1, 김태준1, 이정아1, 이승순1, 고성혜2, 김태영3, 김한성4
1한림대학교 의과대학 한림대학교성심병원 내과
2한림대학교 의과대학 한림대학교성심병원 영상의학과
3한림대학교 의과대학 한림대학교성심병원 정형외과
4한림대학교 의과대학 한림대학교성심병원 진단검사의학과
A Case of Acute Osteomyelitis of the Femur Caused by Nalidixic-Acid-Resistant Salmonella enteritidis
Seong Kyun Na1, Tae Jun Kim1, Jeong-a Lee1, Seung Soon Lee1, Sung-Hye Koh2, Tae-Young Kim3, Han-Sung Kim4
1Departments of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea
2Departments of Radiology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea
3Departments of Orthopedic Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea
4Departments of Laboratory Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea
Corresponding Author: Seung Soon Lee ,Tel: +82-31-380-3724, Fax: +82-31-381-3724, Email: hushh93@hallym.or.kr
Received: May 21, 2014;   Revised: June 13, 2014;   Accepted: July 22, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Infection with nontyphoidal Salmonella most often results in self-limited acute gastroenteritis. However, occasionally it causes bacteremia and localized infection requiring antibiotic treatment. A third-generation cephalosporin or fluoroquinolone is often the first choice of antibiotic. However, there has been an increase in nalidixic-acid-resistant nontyphoidal Salmonella with decreased fluoroquinolone susceptibility. Although there have been many cases reported of nontyphoidal Salmonella, no cases of nalidixic-acid-resistant nontyphoidal Salmonella have been reported in Korea. Here, we report on the case of a 61-year-old man with a diagnosis of acute osteomyelitis and periosteal abscess of the femur caused by nalidixic-acid-resistant Salmonella enteritidis. He was treated successfully with prolonged administration of a high-dose of ciprofloxacin and drainage of the abscess.
Keywords: Salmonella enteritidis; Osteomyelitis; Nalidixic acid; Drug resistance
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