The Korean Journal of Medicine 2015;88(1):106-109.
Published online January 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.1.106   
Benign Lymphoepithelial Cyst of the Parotid Gland as an Initial Manifestation of Human Immunodeficiency Virus Infection
Shinhye Cheon, Sun Hee Na, Eun-young Nam, Myoung Jin Lee, Younghee Jung, Moon Suk Kim, Nam Joong Kim
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
귀밑샘 양성 림프상피낭으로 발현한 사람면역결핍바이러스 감염 1예
천신혜, 나선희, 남은영, 이명진, 정영희, 김문석, 김남중
서울대학교 의과대학 내과학교실
Correspondence: 
Nam Joong Kim, Tel: +82-2-2072-0835, Fax: +82-2-762-9662, Email: molder@unitel.co.kr
Received: 10 March 2014   • Revised: 7 April 2014   • Accepted: 26 May 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Benign lymphoepithelial cysts are rare, and are associated with swelling of the salivary glands (usually the parotid gland). The cytopathological features include lymphoid hyperplasia with an epithelial component, exhibiting cystic and proliferative changes. Development of a benign lymphoepithelial cyst commonly precedes acquisition of acquired immunodeficiency syndrome, but may also be the initial clinical manifestation of human immunodeficiency virus (HIV) infection. A 43 year-old male presented with a slowly growing multilocular cystic mass in his right cheek. Computed tomography of the neck revealed a well-circumscribed cystic lesion in the bilateral parotid glands. A provisional diagnosis of a benign lymphoepithelial cyst associated with HIV infection was made, and Western blotting confirmed the HIV infection. Three months after initiation of antiretroviral therapy, the parotid swelling was completely resolved. We report this case to suggest that clinicians should consider the possibility of HIV infection when patients present with benign lymphoepithelial cysts of the parotid gland.
Key Words: Parotid gland; Cyst; Human immunodeficiency virus (HIV)


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