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Korean J Med > Volume 87(5); 2014 > Article
The Korean Journal of Medicine 2014;87(5): 609-614.
변연대 B세포 림프종에 동반된 초승달사구체신염 1예
이용진2, 류현진2, 박지인2, 이정표1,2, 임춘수1,2, 문경철3, 오윤규1,2
1서울대학교 보라매병원 내과
2서울대학교 의과대학 내과학교실
3서울대학교 의과대학 병리학교실
A Case of Crescentic Glomerulonephritis and Marginal Zone B-cell Lymphoma
YongJin Yi2, HyunJin Ryu2, Ji In Park2, Jung Pyo Lee1,2, Chun Soo Lim1,2, Kyung-Chul Moon3, Yun Kyu Oh1,2
1Department of Internal Medicine, Seoul National University, Boramae Medical Center, Seoul, Korea
2Departments of Internal Medicine, Seoul National University, Boramae Medical Center, Seoul; Departments of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
3Departments of Pathology, Seoul National University College of Medicine, Seoul, Korea
Corresponding Author: Yun Kyu Oh ,Tel: +82-2-870-2219, Fax: +82-2-870-3863, Email: yoonkyu@snu.ac.kr
Received: July 31, 2013;   Revised: October 18, 2013;   Accepted: November 25, 2013.
This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Secondary rapidly progressive glomerulonephritis (RPGN) can be caused by many diseases and conditions, including vasculitis, systemic rheumatic diseases, infections, drugs and malignancies. Among the secondary RPGNs, malignancy-associated RPGN is extremely rare and causes renal function deterioration within several weeks to months. Thus, timely immunosuppressant therapy can improve renal outcome. Herein, we describe a case of RPGN detected simultaneously with marginal zone B-cell lymphoma. An 82-year-old male patient, who presented generalized edema and oliguria, was diagnosed with crescentic glomerulonephritis and marginal B-cell lymphoma. After the patient was given methylprednisolone pulse therapy, renal function was restored and hemodialysis was successfully discontinued without complications.
Keywords: Crescentic glomerulonephritis; Rapidly progressive glomerulonephritis; Marginal zone B-cell lymphoma
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